Search | Global Index Medicus

Selecting candidate antigens for malaria vaccines.

Kidson, C; Saul, A; Schofield, L; Upcroft, J; Don, M; Read, D; Myler, P; Castelino, D; Chiu, S; Ingram, L.

Asian Pac J Allergy Immunol ; 1984 Dec; 2(2): 325-8

Article in English | IMSEAR | ID: sea-36889

Subject(s)

Animals , Antibodies, Monoclonal/immunology , Antigens, Protozoan/genetics , Cloning, Molecular , Epitopes , Humans , Malaria/immunology , Mice , Peptides/chemical synthesis , Plasmodium/genetics , Vaccines/immunology

Ovalocytosis in Papua New Guinea -- dominantly inherited resistance to malaria.

Castelino, D; Saul, A; Myler, P; Kidson, C; Thomas, H; Cooke, R.

Southeast Asian J Trop Med Public Health ; 1981 Dec; 12(4): 549-55

Article in English | IMSEAR | ID: sea-32473

ABSTRACT

Analysis of ovalocytosis in families has demonstrated dominant inheritance. This conclusion is based on finding ovalocytic children of ovalocytic Melanesian mothers and normocytic Caucasian fathers. Inheritance of resistance to thermal deformation and to crenation upon storage correlated with inheritance of ovalocytic erythrocyte morphology. The latter was associated with in vitro resistance to invasion by P. falciparum.

Subject(s)

Elliptocytosis, Hereditary/genetics , Erythrocytes/cytology , Female , Genes, Dominant , Humans , Immunity, Innate , Malaria/immunology , Male , Papua New Guinea , Pedigree

Subject(s)

ABSTRACT

Subject(s)

SEND TO:

SELECTION OF CITATIONS

SEARCH DETAIL